Pubblicazione Scopus: Achillea millefolium L.: A comprehensive review of its phytochemistry and pharmacological properties

Authors: D. Prisa 1 (*), A. Jamal 2

1 CREA Research Centre for Vegetable and Ornamental Crops, Council for Agricultural Research and Economics, Via dei Fiori 8, 51012 Pescia, PT, Italy.

2 Department of Soil and Environmental Sciences, Faculty of Crop

Production Sciences, The University of Agriculture, Peshawar 25130,

Pakistan.

Key words: Antioxidant activity, essential oils, ethnopharmacology, flavonoids, wound healing.

Abstract: Achillea millefolium L., commonly known as yarrow, is a perennial herb traditionally used in various cultures for its therapeutic properties. Belonging to the Asteraceae family, it has gained attention for its rich phytochemical composition, including flavonoids, terpenoids, sesquiterpene lactones, phenolic acids, and essential oils. These bioactive compounds contribute to a wide range of pharmacological activities such as antiinflammatory, antimicrobial, antioxidant, antispasmodic, and wound­ healing effects. Ethnobotanical use of yarrow includes treatment of gastrointestinal disorders, skin injuries, menstrual irregularities, and respiratory infections. Modern preclinical studies have substantiated many of these traditional claims, although clinical validation remains limited. Additionally, its essential oil components show potential in cosmetic and food industries due to their preservative and aromatic properties. Despite its therapeutic promise, concerns related to allergic reactions and toxicity at high doses, particularly from thujone­ containing oils, warrant further safety assessment. This review aims to consolidate current scientific knowledge on A. millefolium, highlighting its pharmacological relevance, phytochemical diversity, and future potential in evidence­ based herbal medicine and natural product development.

Link: https://oaj.fupress.net/index.php/ahs

Doi: 10.36253/ahsc-18140