Research into environmentally friendly methods for controlling nematodes in agricultural crops has gained significant momentum in recent years. This growing interest reflects a broader shift toward more ecologically responsible agricultural practices—ones that prioritize natural biological mechanisms, preserve soil fertility, and protect biodiversity. Increasing consumer demand for high-quality, chemical-free produce has further accelerated this transition. Among the many pests affecting crop production, phytoparasitic nematodes are some of the most destructive, particularly in vegetable crops, where they are responsible for substantial yield losses each year. Traditionally, synthetic pesticides have been the primary means of managing nematode infestations. However, their widespread use has led to considerable environmental concerns, including soil degradation, groundwater contamination, and harm to non-target organisms. Moreover, the effectiveness of many synthetic compounds diminishes over time due to soil interactions and the emergence of resistant nematode populations. Regulatory restrictions on soil fumigants—some of the few chemicals capable of penetrating deep into the soil—have also prompted the search for safer alternatives. As a result, research has increasingly focused on sustainable control strategies that integrate agronomic, biological, and natural solutions. Plant-based products, in particular, have shown considerable promise. These natural compounds exhibit strong nematicidal properties while maintaining a low environmental footprint. Their limited persistence in soil and low toxicity to humans, animals, and non-target plant species make them ideal candidates for sustainable pest management. Furthermore, the complex chemical makeup of plant-derived nematicides—often composed of multiple active ingredients—reduces the likelihood of nematodes developing resistance, a common issue with repeated synthetic pesticide applications. Numerous studies support the efficacy of these botanical alternatives. By preserving soil health and enhancing plant resilience, such approaches contribute not only to pest control but also to long-term agricultural sustainability and productivity.